Article
Identification of HLA-A*0201-restricted T cell epitopes derived from the novel overexpressed tumor antigen calcium-activated chloride channel 2.
Journal of immunology (Baltimore, Md. : 1950) - 1 Jul 2002
Konopitzky Renate, König Ulrich, Meyer Ralf G, Sommergruber Wolfgang, Wölfel Thomas, Schweighoffer Tamás
Abstract excerpt
Vaccination against tumor Ags may become a promising treatment modality especially in cancer types where other therapeutic approaches fail. However, diversity of tumors requires that a multitude of Ags become available. Differential expression in normal vs cancerous tissues, both at the mRNA and the protein level, may identify Ag candidates. We have previously compared transcripts from squamous cell lung cancer...
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