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Article

Polymorphisms of DNA repair gene XRCC1 in squamous cell carcinoma of the head and neck.

Carcinogenesis - 1 Nov 1999

Sturgis E M, Castillo E J, Li L, Zheng R, Eicher S A, Clayman G L, Strom S S, Spitz M R, Wei Q

Abstract excerpt

Because reduced DNA repair capacity (phenotype) has been suggested as a risk factor for squamous cell carcinoma of the head and neck (SCCHN), newly-identified DNA repair gene polymorphisms (genotype) may also be implicated in risk. To test this hypothesis, we conducted a case-control study of 203 SCCHN patients and 424 control subjects (matched for age, sex and ethnicity) to investigate the role of two XRCC1...

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Share to Base Sequence
Share to Carcinoma, Squamous Cell
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Genetic

Share to X-ray Repair Cross Complementing Protein 1

Source

Identifiers

PMID: 10545415
DOI: 10.1093/carcin/20.11.2125

Genes

XRCC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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