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Article

A variant of the DNA repair gene XRCC3 and risk of squamous cell carcinoma of the head and neck: a case-control analysis.

International journal of cancer - 20 Jun 2002

Shen Hongbing, Sturgis Erich M, Dahlstrom Kristina R, Zheng Yuxin, Spitz Margaret R, Wei Qingyi

Abstract excerpt

Individuals differ in their ability to repair DNA damage induced by carcinogens. Studies have shown that polymorphisms in DNA repair genes contribute to individual variation in DNA repair capacity and cancer risk. In a hospital-based case-control study, we tested the hypothesis that a C to T variant (Thr241Met) of DNA repair gene X-ray repair cross-complementing group 3 (XRCC3) is associated with risk of...

Read the complete abstract on PubMed

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Share to Carcinoma, Squamous Cell
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA-Binding Proteins

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Share to Polymorphism, Single-Stranded Conformational

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Source

Identifiers

PMID: 12115490
DOI: 10.1002/ijc.10413

Genes

XRCC3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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