Article
Activation of heat shock genes is not necessary for protection by heat shock transcription factor 1 against cell death due to a single exposure to high temperatures.
Molecular and cellular biology - 1 Aug 2003
Inouye Sachiye, Katsuki Kensaku, Izu Hanae, Fujimoto Mitsuaki, Sugahara Kazuma, Yamada Shu-Ichi, Shinkai Yoichi, Oka Yoshitomo, Katoh Yumiko, Nakai Akira
Abstract excerpt
Heat shock response, which is characterized by the induction of a set of heat shock proteins, is essential for induced thermotolerance and is regulated by heat shock transcription factors (HSFs). Curiously, HSF1 is essential for heat shock response in mammals, whereas in avian HSF3, an avian-specific factor is required for the burst activation of heat shock genes. Amino acid sequences of chicken HSF1 are highly...
Topics
- Adenoviridae
- Alanine
- Amino Acid Sequence
- Animals
- Avian Proteins
- Blotting, Northern
- Cell Death
- Cell Line
- Chickens
- Chromatography, Gel