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Article

Functional domains of the Rsp5 ubiquitin-protein ligase.

Molecular and cellular biology - 1 Jan 1999

Wang G, Yang J, Huibregtse J M

Abstract excerpt

RSP5, an essential gene of Saccharomyces cerevisiae, encodes a hect domain E3 ubiquitin-protein ligase. Hect E3 proteins have been proposed to consist of two broad functional domains: a conserved catalytic carboxyl-terminal domain of approximately 350 amino acids (the hect domain) and a large, nonconserved amino-terminal domain containing determinants of substrate specificity. We report here the mapping of the...

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Identifiers

PMID: 9858558
DOI: 10.1128/MCB.19.1.342
PMCID: PMC83892

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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