Article
Functional domains of the Rsp5 ubiquitin-protein ligase.
Molecular and cellular biology - 1 Jan 1999
Wang G, Yang J, Huibregtse J M
Abstract excerpt
RSP5, an essential gene of Saccharomyces cerevisiae, encodes a hect domain E3 ubiquitin-protein ligase. Hect E3 proteins have been proposed to consist of two broad functional domains: a conserved catalytic carboxyl-terminal domain of approximately 350 amino acids (the hect domain) and a large, no...
Topics
- Alleles
- Amino Acid Sequence
- Binding Sites
- Catalysis
- Endosomal Sorting Complexes Required for Transport
- Immunophilins
- Ligases
- Molecular Sequence Data
- Saccharomyces cerevisiae Proteins
- Structure-Activity Relationship
- Substrate Specificity
- Tacrolimus Binding Proteins
- Ubiquitin-Protein Ligase Complexes
- Ubiquitin-Protein Ligases
- Ubiquitins