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Article

Common variants at the PCOL2 and Sp1 binding sites of the COL1A1 gene and their interactive effect influence bone mineral density in Caucasians.

Journal of medical genetics - 1 Oct 2004

Liu P-Y, Lu Y, Long J-R, Xu F-H, Shen H, Recker R R, Deng H-W

Abstract excerpt

BACKGROUND: Osteoporosis, mainly characterised by low bone mineral density (BMD), is a serious public health problem. The collagen type I alpha 1 (COL1A1) gene is a prominent candidate gene for osteoporosis. Here, we examined whether genetic variants at the COL1A1 gene can influence BMD variation...

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Source

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Identifiers

PMID: 15466008
DOI: 10.1136/jmg.2004.019851
PMCID: PMC1735608

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15466008-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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