Article
Polymorphism in the type I collagen (COLIA1) gene and risk of fractures in postmenopausal women.
Bone - 1 Jan 2002
Bernad M, Martinez M E, Escalona M, González M L, González C, Garcés M V, Del Campo M T, Martín Mola E, Maderò R, Carreñò L
Abstract excerpt
Twin and family studies have demonstrated that a large part of a population's variance in bone mineral density (BMD) is attributable to genetic factors. A polymorphism in the collagen type I alpha1 (COLIA1) gene has recently been associated with low bone mass and fracture incidence. We analyzed the relationship between COLIA1 gene polymorphism, lumbar spine and hip BMD, and fracture prevalence in a population of...
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