Article
Genetic strategy for analyzing specificity of dimer formation: Escherichia coli cyclic AMP receptor protein mutant altered in its dimerization specificity.
Genes & development - 1 Dec 1995
Joung J K, Chung E H, King G, Yu C, Hirsh A S, Hochschild A
Abstract excerpt
Many transcriptional regulators function in homo- or heterodimeric combinations. The same protein can carry out distinct regulatory functions depending on the partner with which it associates. Here, we describe a mutant of the Escherichia coli cAMP receptor protein (CRP) that has an altered dimer...
Topics
- Amino Acid Sequence
- Bacteriophages
- Base Sequence
- Electrophoresis
- Escherichia coli
- Models, Molecular
- Molecular Sequence Data
- Mutation
- Protein Conformation
- Receptors, Cyclic AMP
- Recombinant Fusion Proteins