Article
Heparinase Is Essential for Pseudomonas aeruginosa Virulence during Thermal Injury and Infection.
Infection and immunity - 1 Jan 2018
Dzvova Nyaradzo, Colmer-Hamood Jane A, Griswold John A, Hamood Abdul N
Abstract excerpt
The opportunistic pathogen Pseudomonas aeruginosa is a major cause of sepsis in severely burned patients. If it is not eradicated from the wound, it translocates to the bloodstream, causing sepsis, multiorgan failure, and death. We recently described the P. aeruginosa heparinase-encoding gene, hepP, whose expression was significantly enhanced when P. aeruginosa strain UCBPP_PA14 (PA14) was grown in whole blood...
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