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Pseudomonas aeruginosa wound infection involves activation of its iron acquisition system in response to fascial contact

24 Mar 2015

Abstract excerpt

BACKGROUND: Wound infections are traditionally thought to occur when microbial burden exceeds the innate clearance capacity of host immune system. Here, we introduce the idea that the wound environment itself plays a significant contributory role to wound infection. METHODS: We developed a clinically relevant murine model of soft tissue infection to explore the role of activation of microbial virulence in...

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PMID: 25807409
DOI: 10.1097/ta.0000000000000574

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