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Article

Functional interaction between GCN5 and polyamines: a new role for core histone acetylation.

The EMBO journal - 15 Oct 1999

Pollard K J, Samuels M L, Crowley K A, Hansen J C, Peterson C L

Abstract excerpt

Polyamines are organic polycations essential for a wide variety of cellular functions, including nuclear integrity and chromosome condensation. Here we present genetic evidence that depletion of cellular polyamines partially alleviates the defects in HO and SUC2 expression caused by inactivation of the GCN5 histone acetyltransferase. In addition, the combination of polyamine depletion and a sin(-) allele of the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 10523306
DOI: 10.1093/emboj/18.20.5622
PMCID: PMC1171630

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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