Article
Interindividual variation in mitotic recombination.
American journal of human genetics - 1 Nov 1999
Holt D, Dreimanis M, Pfeiffer M, Firgaira F, Morley A, Turner D
Abstract excerpt
Mitotic recombination (MR) between homologous chromosomes is a mutational event that results in loss of heterozygosity in half of the segregants at mitosis. Loss of heterozygosity may have important biological consequences. The purpose of this study was to describe human variation in the spontaneous frequency of MR. Using an immunoselection technique for isolating the somatic mutations that result in loss of...
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