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Article

Nonhomologous DNA end joining in cell-free systems.

European journal of biochemistry - 1 Nov 1999

Labhart P

Abstract excerpt

Double strand DNA breaks are usually caused by ionizing radiation and radiomimetic drugs, but can also occur under normal physiological conditions during double strand break-induced recombination, such as the rearrangement of T-cell receptor and immunoglobulin genes during lymphoid development or the mating type switching in yeast. The main repair mechanism for double strand breaks in higher eukaryotes is...

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Identifiers

PMID: 10518778
DOI: 10.1046/j.1432-1327.1999.00805.x

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