Nonhomologous DNA end joining in cell-free systems.

doi:10.1046/j.1432-1327.1999.00805.x

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Article

Nonhomologous DNA end joining in cell-free systems.

European journal of biochemistry - 1 Nov 1999

Labhart P

Abstract excerpt

Double strand DNA breaks are usually caused by ionizing radiation and radiomimetic drugs, but can also occur under normal physiological conditions during double strand break-induced recombination, such as the rearrangement of T-cell receptor and immunoglobulin genes during lymphoid development or the mating type switching in yeast. The main repair mechanism for double strand breaks in higher eukaryotes is...

Topics

Animals
Cattle
Cell Nucleus
Cell-Free System
Cytoplasm
DNA Damage
DNA Repair
Female
Humans
Immunologic Techniques
In Vitro Techniques
Mutation
Oocytes
Xenopus

Source

Open in PubMed

Identifiers

PMID: 10518778
DOI: 10.1046/j.1432-1327.1999.00805.x

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