Article
Role of non-homologous end joining (NHEJ) in maintaining genomic integrity.
DNA repair - 8 Sept 2006
Burma Sandeep, Chen Benjamin P C, Chen David J
Abstract excerpt
Of the various types of DNA damage that can occur within the mammalian cell, the DNA double strand break (DSB) is perhaps the most dangerous. DSBs are typically induced by intrinsic sources such as the by products of cellular metabolism or by extrinsic sources such as X-rays or gamma-rays and chemotherapeutic drugs. It is becoming increasing clear that an inability to respond properly to DSBs will lead to genomic...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.