Article
A Xenopus protein related to hnRNP I has a role in cytoplasmic RNA localization.
Molecular cell - 1 Sept 1999
Cote C A, Gautreau D, Denegre J M, Kress T L, Terry N A, Mowry K L
Abstract excerpt
Cytoplasmic localization of mRNA molecules is a powerful mechanism for generating cell polarity. In vertebrates, one paradigm is localization of Vg1 RNA within the Xenopus oocyte, a process directed by recognition of a localization element within the Vg1 3' UTR. We show that specific base changes within the localization element abolish both localization in vivo and binding in vitro by a single protein, VgRBP60....
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