Article
A consensus RNA signal that directs germ layer determinants to the vegetal cortex of Xenopus oocytes.
Developmental biology - 1 Aug 2002
Bubunenko Mikhail, Kress Tracy L, Vempati Uma Devi, Mowry Kimberly L, King Mary Lou
Abstract excerpt
RNA localization is an important mechanism for generating cellular diversity and polarity in the early embryo. In Xenopus, the correct localization of the RNA encoding the T-box transcription factor VegT is essential for the correct spatial organization and identity of endoderm and mesoderm. Although localization signals in the 3' UTR have been identified for many localized RNAs, insight into what constitutes an...
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