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Article

Localization of Xenopus Vg1 mRNA by Vera protein and the endoplasmic reticulum.

Science (New York, N.Y.) - 16 May 1997

Deshler J O, Highett M I, Schnapp B J

Abstract excerpt

In many organisms, pattern formation in the embryo develops from the polarized distributions of messenger RNAs (mRNAs) in the egg. In Xenopus, the mRNA encoding Vg1, a growth factor involved in mesoderm induction, is localized to the vegetal cortex of oocytes. A protein named Vera was shown to be involved in Vg1 mRNA localization. Vera cofractionates with endoplasmic reticulum (ER) membranes, and endogenous Vg1...

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Identifiers

PMID: 9148809
DOI: 10.1126/science.276.5315.1128

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Localization of Xenopus Vg1 mRNA by Vera protein and the endoplasmic reticulum.PMID 9148809Read ↗

PTB/hnRNP I is required for RNP remodeling during RNA localization in Xenopus oocytes.Semantic proximity Read ↗

A Xenopus protein related to hnRNP I has a role in cytoplasmic RNA localization.Semantic proximity Read ↗

Two copies of a subelement from the Vg1 RNA localization sequence are sufficient to direct vegetal localization in Xenopus oocytes.Semantic proximity Read ↗

A consensus RNA signal that directs germ layer determinants to the vegetal cortex of Xenopus oocytes.Semantic proximity Read ↗

Vg1 has specific processing requirements that restrict its action to body axis patterning centers.Semantic proximity Read ↗

The 36-kilodalton embryonic-type cytoplasmic polyadenylation element-binding protein in Xenopus laevis is ElrA, a member of the ELAV family of RNA-binding proteins.Semantic proximity Read ↗

Functional dissection of the RNA signal sequence responsible for vegetal localization of XGrip2.1 mRNA in Xenopus oocytes.Semantic proximity Read ↗

Transcriptome and Proteome Analysis Revealed Key Pathways Regulating Final Stage of Oocyte Maturation of the Turkey (Meleagris gallopavo)Semantic proximity Read ↗

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