Article
The RNA-binding protein Vg1 RBP is required for cell migration during early neural development.
Development (Cambridge, England) - 1 Dec 2003
Yaniv Karina, Fainsod Abraham, Kalcheim Chaya, Yisraeli Joel K
Abstract excerpt
After mid-blastula transition, populations of cells within the Xenopus embryo become motile. Using antisense morpholino oligonucleotides, we find that Vg1 RBP, an RNA-binding protein implicated in RNA localization in oocytes, is required for the migration of cells forming the roof plate of the neural tube and, subsequently, for neural crest migration. These cells are properly determined but remain at their site...
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