Astroglial differentiation of cortical precursor cells triggered by activation of the cAMP-dependent signaling pathway.

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Article

Astroglial differentiation of cortical precursor cells triggered by activation of the cAMP-dependent signaling pathway.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 15 Oct 1999

McManus M F, Chen L C, Vallejo I, Vallejo M

Abstract excerpt

In the developing brain, differentiation of neural precursors into neurons or glial cells occurs in response to neurotrophic factors acting on the cell surface. Intracellular signaling mechanisms that relay information to initiate differentiative responses of neural precursor cells are poorly understood. To investigate whether stimulation of the cAMP-dependent signaling pathway participates in differentiative...

Topics

Animals
Antigens, Polyomavirus Transforming
Astrocytes
Cell Differentiation
Cell Division
Cell Line, Transformed
Cells, Cultured
Cerebral Cortex
Culture Media
Cyclic AMP

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Gene Expression Regulation

Phenotype

Rats

Rats, Sprague-Dawley

Signal Transduction

Stem Cells

Temperature

Source

Open in PubMed Open full text

Identifiers

PMID: 10516318
PMCID: PMC6782746

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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