Article
Elevated intracellular levels of cAMP induce olfactory ensheathing cells to express GAL-C and GFAP but not MBP.
Glia - 1 Feb 1995
Doucette R, Devon R
Abstract excerpt
The primary olfactory pathway contains non-myelinating glial cells, called ensheathing cells, that exhibit a variety of phenotypes depending on their immediate environment. In vivo, these cells normally possess a mixture of astrocyte- and Schwann cell-specific phenotypic features. When co-cultured with dorsal root ganglion neurons, their phenotype can become more like that of a myelinating Schwann cell. The...
Topics
- Animals
- Bucladesine
- Cells, Cultured
- Colforsin
- Cyclic AMP
- Female
- Galactosylceramides
- Glial Fibrillary Acidic Protein
- Myelin Basic Protein
- Neuroglia
- Olfactory Pathways
- Oligodendroglia