Article
Cyclin-dependent kinase inhibitor p27kip1 is expressed at high levels in cells that express a myelinating phenotype.
Journal of neuroscience research - 1 Nov 1997
Friessen A J, Miskimins W K, Miskimins R
Abstract excerpt
Terminal cellular differentiation is generally accompanied by exit from the cell cycle but the molecular basis of how the two events are coupled is poorly understood. In the central nervous system (CNS) the terminally differentiated, non-proliferating myelin-synthesizing cells, oligodendrocytes,...
Topics
- 1-Methyl-3-isobutylxanthine
- Animals
- Brain
- Cell Cycle
- Cell Cycle Proteins
- Cell Division
- Cell Line
- Cells, Cultured
- Cyclic AMP
- Cyclin D
- Cyclin E
- Cyclin-Dependent Kinase Inhibitor p27
- Cyclin-Dependent Kinases
- Cyclins
- Kinetics
- Microtubule-Associated Proteins
- Myelin Basic Protein
- Oligodendroglia
