Article
HLA-DRB and HLA-DQB loci in the genetic susceptibility to develop glaucoma in Mexicans.
American journal of ophthalmology - 1 Sept 1999
Gil-Carrasco F, Vargas-Alarcón G, Zúñiga J, Tinajero-Castañeda O, Hernández-Martinez B, Hernández-Pacheco G, Rodríguez-Reyna T S, Hesiquio R, Gamboa R, Granados J
Abstract excerpt
PURPOSE: Glaucoma is a clinically heterogeneous disease with a pathophysiology that may include genetic susceptibility, possibly associated with an immunologic disorder. The aim of this study was to determine whether the DNA polymorphisms located in the HLA-DRB1 and HLA-DQB1 genes show a specific association pattern in Mexican mestizo patients with primary open-angle glaucoma. METHODS: This was a cross-sectional,...
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