Association of HLA-DR3 and HLA-DR4 with sinonasal polyposis in Mexican Mestizos.

doi:10.1016/j.otohns.2006.01.009

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Article

Association of HLA-DR3 and HLA-DR4 with sinonasal polyposis in Mexican Mestizos.

Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery - 1 Jul 2006

Ramírez-Anguiano Jaqueline, Yamamoto-Furusho Jesús K, Barquera Rodrigo, Beltrán Olga, Granados Julio

Abstract excerpt

OBJECTIVE: The pathogenesis of sinonasal polyposis (SNP) is not clear; it has been suggested that it is polygenic and multifactorial. The major histocompatibility complex is a useful tool to predict genetic susceptibility to diseases, especially to autoimmune diseases. Since such susceptibility is influenced by ethnicity, it is necessary to have a wide knowledge of the structure of the population to which the...

Topics

Adult
Aged
Alleles
DNA
Female
Gene Expression
Gene Frequency
HLA-DR3 Antigen
HLA-DR4 Antigen
Humans
Incidence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Mexico

Middle Aged

Nasal Polyps

Polymerase Chain Reaction

Retrospective Studies

Source

Open in PubMed

Identifiers

PMID: 16815190
DOI: 10.1016/j.otohns.2006.01.009

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