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Article

The role of major histocompatibility complex alleles in the susceptibility of Brazilian patients to develop the myogenic type of Graves' orbitopathy.

Thyroid : official journal of the American Thyroid Association - 1 Apr 2008

Akaishi Patricia Mitiko Santello, Cruz Antonio Augusto Velasco, Silva Fabricio Leon Mascaro, Rodrigues Maria de Lourdes Veronesi, Maciel Lea Maria Zanini, Donadi Eduardo Antonio

Abstract excerpt

OBJECTIVE: To assess the frequency of the genetic markers HLA-DRB1 and DQB1 in patients with Graves' orbitopathy (GO) with and without extraocular muscle involvement. DESIGN: The frequencies of class II HLA-DRB1 and DQB1 allele groups were determined for 81 Brazilian patients with GO and 161 normal subjects. The patients were divided into myogenic and nonmyogenic groups based on the clinical characteristics of...

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Source

Identifiers

PMID: 18352820
DOI: 10.1089/thy.2007.0194

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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