Article
Association study of multiple gene polymorphisms with the risk of adult-onset primary open-angle glaucoma in a Mexican population.
Experimental eye research - 1 Feb 2013
Buentello-Volante Beatriz, Elizondo-Olascoaga Celia, Miranda-Duarte Antonio, Guadarrama-Vallejo Dalia, Cabral-Macias Jesús, Zenteno Juan C
Abstract excerpt
The aim of this study was to investigate the association of multiple primary open-angle glaucoma (POAG)-risk alleles in a Mexican population for the first time. Genotyping was performed for a total of 26 previously associated alleles located in 11 different genes, including MYOC, CYP1B1, OPTN, IL1A, TNF, OPA1, EDNRA, AGTR2, MTHFR, GSTM1, and GSTT1. The frequencies of these variants were compared in a group of 218...
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