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Article

Association of HLA-DRB1*16 with chronic discoid lupus erythematosus in Mexican mestizo patients.

Clinical and experimental dermatology - 1 Jul 2007

López-Tello A, Rodríguez-Carreón A A, Jurado F, Yamamoto-Furusho J K, Castillo-Vázquez M, Chávez-Muñoz C, Salgado N, Arellano-Campos O, Vargas-Alarcón G, Granados J

Abstract excerpt

BACKGROUND: Chronic discoid lupus erythematosus (CDLE) is present in 15-30% of patients with systemic lupus erythematosus (SLE). Approximately 5% of CDLE cases can evolve to SLE at some stage of the disease. AIM: The aim of this study was to determine gene frequencies of HLA-DRB1 alleles in Mexican mestizo patients with CDLE, irrespective of the presence of systemic disease. METHODS: The study comprised 28...

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PMID: 17376212
DOI: 10.1111/j.1365-2230.2007.02391.x

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