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Article

Functional screening of an asthma QTL in YAC transgenic mice.

Nature genetics - 1 Oct 1999

Symula D J, Frazer K A, Ueda Y, Denefle P, Stevens M E, Wang Z E, Locksley R, Rubin E M

Abstract excerpt

Many quantitative trait loci (QTLs) contributing to genetically complex conditions have been discovered, but few causative genes have been identified. This is mainly due to the large size of QTLs and the subtle connection between genotype and quantitative phenotype associated with these conditions. Transgenic mice have been successfully used to analyse well-characterized genes suspected of contributing to...

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PMID: 10508526
DOI: 10.1038/13880

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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