Article
Positional identification of an asthma susceptibility gene on human chromosome 5q33.
American journal of respiratory and critical care medicine - 15 Jul 2005
Noguchi Emiko, Yokouchi Yukako, Zhang Jiang, Shibuya Kazuko, Shibuya Akira, Bannai Makoto, Tokunaga Katsushi, Doi Hitomi, Tamari Mayumi, Shimizu Makiko, Shirakawa Taro, Shibasaki Masanao, Ichikawa Kunio, Arinami Tadao
Abstract excerpt
RATIONALE: Asthma is a common respiratory disease with complex genetic components. We previously reported strong evidence for linkage between mite-sensitive asthma and markers on chromosome 5q33. This area of linkage includes a region homologous to a mouse area that contains a locus involved in regulation of airway hyperreactivity. OBJECTIVE: The aim of the present study is to identify asthma susceptibility genes...
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