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Article

Variation in conserved non-coding sequences on chromosome 5q and susceptibility to asthma and atopy.

Respiratory research - 10 Dec 2005

Donfack Joseph, Schneider Daniel H, Tan Zheng, Kurz Thorsten, Dubchak Inna, Frazer Kelly A, Ober Carole

Abstract excerpt

BACKGROUND: Evolutionarily conserved sequences likely have biological function. METHODS: To determine whether variation in conserved sequences in non-coding DNA contributes to risk for human disease, we studied six conserved non-coding elements in the Th2 cytokine cluster on human chromosome 5q31 in a large Hutterite pedigree and in samples of outbred European American and African American asthma cases and...

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Identifiers

PMID: 16336695
DOI: 10.1186/1465-9921-6-145
PMCID: PMC1325232

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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