Article
Gene conversion confined to a direct repeat of the acceptor splice site generates allelic diversity at human glycophorin (GYP) locus.
The Journal of biological chemistry - 15 Feb 1992
Huang C H, Kikuchi M, McCreary J, Blumenfeld O O
Abstract excerpt
The glycophorin locus (GYP) on the long arm of chromosome 4 encodes antigens of the MNSs blood group system and displays considerable allelic variation among human populations. The genomic structure and organization of a variant glycophorin allele specifying a novel Miltenberger (Mi)-related phen...
Topics
- Alleles
- Amino Acid Sequence
- Blotting, Southern
- Chromosomes, Human, Pair 4
- DNA
- Gene Amplification
- Gene Conversion
- Genetic Variation
- Glycophorins
- Heterozygote
- Humans
- Leukocytes
- MNSs Blood-Group System
- Molecular Sequence Data
- RNA Splicing
- Repetitive Sequences, Nucleic Acid
- Restriction Mapping
- Sequence Homology, Nucleic Acid