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Presence of Donor- and Recipient-derived DNA in Cell-free Urine Samples of Renal Transplantation Recipients: Urinary DNA Chimerism

1 Oct 1999

Abstract excerpt

BACKGROUND: Previous studies have indicated that microchimerism is present in body tissues, peripheral blood, and plasma of recipients after organ transplantation. We hypothesize that donor-derived DNA may also be present in cell-free urine of renal transplant recipients and that the concentrations of urine DNA may be correlated with graft rejection. METHODS: Thirty-one female patients who had renal...

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Share to Genomic variations and chromosomal abnormalities
Share to Prenatal Screening and Diagnostics
Share to Renal Transplantation Outcomes and Treatments

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PMID: 10508119
DOI: 10.1093/clinchem/45.10.1741

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