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Plasma donor-derived cell-free DNA kinetics after kidney transplantation using a single tube multiplex PCR assay

6 Dec 2018

Abstract excerpt

BACKGROUND: After transplantation, cell-free DNA derived from the donor organ (ddcfDNA) can be detected in the recipient's circulation. We aimed to quantify ddcfDNA levels in plasma of kidney transplant recipients thereby investigating the kinetics of this biomarker after transplantation and determining biological variables that influence ddcfDNA kinetics in stable and non-stable patients. MATERIALS AND METHODS:...

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PMID: 30521549
DOI: 10.1371/journal.pone.0208207

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