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The use of plasma donor-derived, cell-free DNA to monitor acute rejection after kidney transplantation

13 Apr 2019

Abstract excerpt

BACKGROUND: After transplantation, cell-free deoxyribonucleic acid (DNA) derived from the donor organ (ddcfDNA) can be detected in the recipient's circulation. We aimed to investigate the role of plasma ddcfDNA as biomarker for acute kidney rejection. METHODS: From 107 kidney transplant recipients, plasma samples were collected longitudinally after transplantation (Day 1 to 3 months) within a multicentre set-up....

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PMID: 31106364
DOI: 10.1093/ndt/gfz091

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