Article
Exposed loop domains of complexed 14-3-3 proteins contribute to structural diversity and functional specificity.
Plant physiology - 1 Feb 2006
Sehnke Paul C, Laughner Beth, Cardasis Helene, Powell David, Ferl Robert J
Abstract excerpt
The 14-3-3 family of proteins functions through protein:phosphoprotein interactions, the nature of which has been elucidated using x-ray crystallography. However, some key structural features in nonconserved regions have yet to be fully resolved, leaving open questions regarding the functional selectivity of 14-3-3 family members for diverse clients. In an effort to study surface accessible structural features in...
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