Article
Heteromeric kainate receptors formed by the coassembly of GluR5, GluR6, and GluR7.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 1 Oct 1999
Cui C, Mayer M L
Abstract excerpt
In the CNS kainate subtype glutamate receptors (GluRs) are likely to be heteromeric assemblies containing multiple gene products. However, although recombinant kainate receptors from the GluR5-GluR7 gene family have been studied extensively in their homomeric forms, there have been no tests to determine whether these subunits can coassemble with each other. We used the GluR5 selective agonists...
Topics
- Alanine
- Alternative Splicing
- Cell Line
- Excitatory Amino Acid Agonists
- Genetic Variation
- Humans
- Isoxazoles
- Kainic Acid
- Macromolecular Substances
- Membrane Potentials
- Mutagenesis, Site-Directed