Article
Glutathione S-transferase M1 and P1 metabolic polymorphism and lung cancer predisposition.
Neoplasma - 1 Jan 2003
Reszka E, Wasowicz W, Rydzynski K, Szeszenia-Dabrowska N, Szymczak W
Abstract excerpt
Individual susceptibility to different environmental agents is expected to be associated with alterations in metabolism of xenobiotics. Thus, genetic polymorphism of glutathione S-transferase (GST) can be recognized as a potential risk modifier in lung cancer development. The distribution of GSTM1 and GSTP1 genotypes was studied in a group of 138 diagnosed lung cancer patients and in 165 controls living in...
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