Article
Use of biomarkers in epidemiology. The example of metabolic susceptibility to cancer.
Toxicology letters - 1 May 1995
Vineis P
Abstract excerpt
This paper examines the methodological problems faced in epidemiological studies which use a particular class of biomarkers, those of genetic susceptibility to cancer. Their use in epidemiology is increasing, they raise special methodological questions and entail particular ethical consequences....
Topics
- Biomarkers
- Cytochrome P-450 CYP2D6
- Cytochrome P-450 Enzyme System
- Debrisoquin
- Disease Susceptibility
- Genetic Predisposition to Disease
- Genotype
- Humans
- Isoenzymes
- Mixed Function Oxygenases
- Neoplasms
- Phenotype