Article
Use of biomarkers in epidemiology. The example of metabolic susceptibility to cancer.
Toxicology letters - 1 May 1995
Vineis P
Abstract excerpt
This paper examines the methodological problems faced in epidemiological studies which use a particular class of biomarkers, those of genetic susceptibility to cancer. Their use in epidemiology is increasing, they raise special methodological questions and entail particular ethical consequences. A list of questions concerning the validity of the studies is discussed. (1) Is the test used to measure the genotype...
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