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Article

Study design in genetic epidemiology: theoretical and practical considerations.

Journal of the National Cancer Institute. Monographs - 1 Jan 1999

Whittemore A S, Nelson L M

Abstract excerpt

Recent advances in molecular genetics have created new opportunities and challenges for genetic epidemiologists. Here we review some of the issues that arise when designing a study involving the genetic epidemiology of chronic diseases of late onset, such as cancer. We discuss two considerations that influence the choice of design. The first consideration is the study's goals. We describe the goals of identifying...

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PMID: 10854488
DOI: 10.1093/oxfordjournals.jncimonographs.a024228

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