Article
Metabolism of xenobiotics and chemical carcinogenesis.
IARC scientific publications - 1 Jan 1999
Lang M, Pelkonen O
Abstract excerpt
In order to avoid the accumulation of harmful xenobiotics in cells, living organisms have developed ways for their elimination. Multiple xenobiotic metabolizing enzymes with variable but partially overlapping catalytic properties play a key role in the elimination process. These enzymes are encoded by superfamilies of genes which, during the course of evolution, have evolved in a way that has made it possible for...
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