Article
Influence of GSTM1 genotypes on anti-BPDE-DNA adduct levels in mononuclear white blood cells of humans exposed to PAH.
International archives of occupational and environmental health - 1 Jul 1999
Pavanello S, Gabbani G, Mastrangelo G, Brugnone F, Maccacaro G, Clonfero E
Abstract excerpt
OBJECTIVE: Association between genetic deletion polymorphism of GSTM1 (*0/*0 or active) and levels of anti (+/-)-r-7,t-8-dihydroxy-t-9,10-oxy-7,8,9,10-tetrahydrobenzo[a]pyrene (anti-BPDE)-DNA adducts in the peripheral blood lymphocyte plus monocyte fraction (LMF) of PAH-exposed subjects was inves...
Topics
- 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide
- Adolescent
- Adult
- Carcinogens
- Chemical Industry
- Chromatography, High Pressure Liquid
- DNA Adducts
- Environmental Exposure
- Environmental Monitoring
- Female
- Genotype
- Glutathione Transferase
- Humans
- Male
- Middle Aged
- Occupational Exposure
- Polycyclic Compounds
- Polymorphism, Genetic