Article
[Individual susceptibility to occupational carcinogens: the evidence from biomonitoring and molecular epidemiology studies].
Giornale italiano di medicina del lavoro ed ergonomia - 1 Jan 2000
Pavanello S, Clonfero E
Abstract excerpt
This paper reviews the literature on the influence of metabolic and DNA repair polymorphisms of biological indicators of genotoxic risk commonly used in biomonitoring occupational exposure to carcinogens. Genetic polymorphisms which influence biomarkers (urinary metabolites, protein and DNA adducts), include P450 cytochromes (CYPs) and glutathione S-transferases (GSTs) in exposure to polycyclic aromatic...
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