Article
Coke oven workers study: the effect of exposure and GSTM1 and NAT2 genotypes on DNA adduct levels in white blood cells and lymphocytes as determined by 32P-postlabelling.
Mutation research - 7 Aug 1998
Binková B, Topinka J, Mracková G, Gajdosová D, Vidová P, Stávková Z, Peterka V, Pilcík T, Rimár V, Dobiás L, Farmer P B, Srám R J
Abstract excerpt
The DNA adduct levels in total white blood cells (WBC) and lymphocytes (LYM) isolated from the blood of the same individuals were evaluated using the 32P-postlabelling assay for bulky aromatic adducts. In this study, 68 male coke oven workers and 56 machines workers as a matched control were enro...
Topics
- Adult
- Arylamine N-Acetyltransferase
- Case-Control Studies
- Coke
- Cotinine
- DNA Adducts
- Genotype
- Glutathione Transferase
- Humans
- Leukocytes
- Logistic Models
- Lymphocytes
- Male
- Middle Aged