Article
Coke oven workers study: the effect of exposure and GSTM1 and NAT2 genotypes on DNA adduct levels in white blood cells and lymphocytes as determined by 32P-postlabelling.
Mutation research - 7 Aug 1998
Binková B, Topinka J, Mracková G, Gajdosová D, Vidová P, Stávková Z, Peterka V, Pilcík T, Rimár V, Dobiás L, Farmer P B, Srám R J
Abstract excerpt
The DNA adduct levels in total white blood cells (WBC) and lymphocytes (LYM) isolated from the blood of the same individuals were evaluated using the 32P-postlabelling assay for bulky aromatic adducts. In this study, 68 male coke oven workers and 56 machines workers as a matched control were enrolled. Personal monitors were used to evaluate exposure to eight carcinogenic PAHs, including B[alpha]P, during an 8-h...
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