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Article

Effects of genetic polymorphisms of metabolic enzymes on cytokinesis-block micronucleus in peripheral blood lymphocyte among coke-oven workers.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Oct 2004

Leng Shuguang, Dai Yufei, Niu Yong, Pan Zufei, Li Xiaohua, Cheng Juan, He Fengsheng, Zheng Yuxin

Abstract excerpt

Exploring the associations between genetic polymorphisms of metabolic enzymes and susceptibility to polycyclic aromatic hydrocarbon (PAH)-induced chromosomal damage is of great significance for understanding PAH carcinogenesis. Cytochrome P450, glutathione S-transferase, microsomal epoxide hydrolase, NAD(P)H:quinone oxidoreductase, and N-acetyltransferase are PAH-metabolizing enzymes. In this study, we genotyped...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15466980

Genes

PAH
GSTM1
GSTP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Effects of genetic polymorphisms of metabolic enzymes on cytokinesis-block micronucleus in peripheral blood lymphocyte among coke-oven workers.PMID 15466980Read ↗

[A study on the inherited susceptibility of chromosomal damage in peripheral blood lymphocytes among coke oven workers].Semantic proximity Read ↗

Suboptimal DNA repair capacity predisposes coke-oven workers to accumulate more chromosomal damages in peripheral lymphocytes.Semantic proximity Read ↗

The effect of relevant genotypes on PAH exposure-related biomarkers.Semantic proximity Read ↗

Association of polymorphisms in AhR, CYP1A1, GSTM1, and GSTT1 genes with levels of DNA damage in peripheral blood lymphocytes among coke-oven workers.Semantic proximity Read ↗

[Association of metabolic and DNA repair enzyme gene polymorphisms and DNA damage in coke-oven workers].Semantic proximity Read ↗

[Association between aryl hydrocarbon receptor gene polymorphisms and chromosomal damage in coke-oven workers].Semantic proximity Read ↗

[Effect of genetic polymorphisms of microsomal epoxide hydrolase on urinary 1-hydroxypyrene levels in coke oven workers].Semantic proximity Read ↗

Associations between 25 lung cancer risk-related SNPs and polycyclic aromatic hydrocarbon-induced genetic damage in coke oven workers.Semantic proximity Read ↗

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[Association between methylenetetrahydrofolate reductase gene haplotypes and the susceptibility of chromosomal damage in coke-oven workers].Semantic proximity Read ↗

Influence of GSTM1, GSTT1, GSTP1, and EPHX gene polymorphisms on DNA adduct level and HPRT mutant frequency in coke-oven workers.Semantic proximity Read ↗

[Association of XRCC1 polymorphisms and chromosomal damage levels in coke-oven workers].Semantic proximity Read ↗

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