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Article

Reversion of human glioblastoma malignancy by U1 small nuclear RNA/ribozyme targeting of scatter factor/hepatocyte growth factor and c-met expression.

Journal of the National Cancer Institute - 15 Sept 1999

Abounader R, Ranganathan S, Lal B, Fielding K, Book A, Dietz H, Burger P, Laterra J

Abstract excerpt

BACKGROUND: Expression of scatter factor (SF), also known as hepatocyte growth factor (HGF), and its receptor, c-met, is often associated with malignant progression of human tumors, including gliomas. Overexpression of SF/HGF in experimental gliomas enhances tumorigenicity and tumor-associated angiogenesis (i.e., growth of new blood vessels). However, the role of endogenous SF/HGF or c-met expression in the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Proto-Oncogene Proteins c-met

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Source

Identifiers

PMID: 10491431
DOI: 10.1093/jnci/91.18.1548

Genes

HGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Reversion of human glioblastoma malignancy by U1 small nuclear RNA/ribozyme targeting of scatter factor/hepatocyte growth factor and c-met expression.PMID 10491431Read ↗

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Circular RNA encoded MET variant promotes glioblastoma tumorigenesisSemantic proximity Read ↗

Gene of the month: METSemantic proximity Read ↗

Role of hepatocyte growth factor activator (HGF activator) in invasive growth of human glioblastoma cells in vivo.Semantic proximity Read ↗

The roles of hepatocyte growth factor/scatter factor and met receptor in human cancers (Review).Semantic proximity Read ↗

Hepatocyte growth factor (HGF) autocrine activation predicts sensitivity to MET inhibition in glioblastomaSemantic proximity Read ↗

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