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HGF/MET Signaling in Malignant Brain Tumors

13 Oct 2020

Abstract excerpt

Hepatocyte growth factor (HGF) ligand and its receptor tyrosine kinase (RTK) mesenchymal-epithelial transition factor (MET) are important regulators of cellular processes such as proliferation, motility, angiogenesis, and tissue regeneration. In healthy adult somatic cells, this ligand and receptor pair is expressed at low levels and has little activity except when tissue injuries arise. In cancer cells, HGF/MET...

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PMID: 33066121
DOI: 10.3390/ijms21207546

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