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Article

Ig heavy chain complex-linked genes influence the immune response in a murine cryptococcal infection.

Journal of immunology (Baltimore, Md. : 1950) - 1 Oct 1999

Lovchik J A, Wilder J A, Huffnagle G B, Riblet R, Lyons C R, Lipscomb M F

Abstract excerpt

A murine pulmonary infection with Cryptococcus neoformans (Cne) has been used to determine mechanisms regulating effective T cell-mediated immunity in the lungs. In BALB/c and C.B-17 mice, following intratracheal deposition of Cne, the fungus initially grows rapidly and is then progressively cleared from the lungs. Cne clearance in C.B-17 mice requires CD4 and CD8 T cells, IFN-gamma, and NO. Clearance in congenic...

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Source

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PMID: 10490991

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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