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Article

Genetic variants of RANTES are associated with serum RANTES level and protection for type 1 diabetes.

Genes and immunity - 1 Oct 2006

Zhernakova A, Alizadeh B Z, Eerligh P, Hanifi-Moghaddam P, Schloot N C, Diosdado B, Wijmenga C, Roep B O, Koeleman B P C

Abstract excerpt

RANTES (regulated on activation, normal T-cell expressed and secreted) is a T-helper type 1 (Th1) chemokine that promotes T-cell activation and proliferation. RANTES is genetically associated with asthma, sarcoidosis and multiple sclerosis. The concentration of RANTES is increased at inflammation sites in different autoimmune diseases. Type 1 diabetes (T1D) is a Th1-mediated disease with complex genetic...

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Identifiers

PMID: 16855620
DOI: 10.1038/sj.gene.6364326

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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