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Identification of sequence-dependent DNA features correlating to activity of DNA sites interacting with proteins.

Bioinformatics (Oxford, England) - 1 Jan 2000

Ponomarenko M P, Ponomarenko J V, Frolov A S, Podkolodny N L, Savinkova L K, Kolchanov N A, Overton G C

Abstract excerpt

MOTIVATION: The commonly accepted statistical mechanical theory is now multiply confirmed by using the weight matrix methods successfully recognizing DNA sites binding regulatory proteins in prokaryotes. Nevertheless, the recent evaluation of weight matrix methods application for transcription factor binding site recognition in eukaryotes has unexpectedly revealed that the matrix scores correlate better to each...

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PMID: 10487875
DOI: 10.1093/bioinformatics/15.7.687

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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