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Article

Mutational signatures and chromosome alteration profiles of squamous cell carcinomas of the vulva.

Experimental & molecular medicine - 9 Feb 2018

Han Mi-Ryung, Shin Sun, Park Hyeon-Chun, Kim Min Sung, Lee Sung Hak, Jung Seung Hyun, Song Sang Yong, Lee Sug Hyung, Chung Yeun-Jun

Abstract excerpt

Vulvar squamous cell carcinoma (SCC) consists of two different etiologic categories: human papilloma virus (HPV)-associated (HPV (+)) and HPV-non-associated (HPV (-)). There have been no genome-wide studies on the genetic alterations of vulvar SCCs or on the differences between HPV (+) and HPV (-) vulvar SCCs. In this study, we performed whole-exome sequencing and copy number profiling of 6 HPV (+) and 9 HPV (-)...

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Share to Carcinoma, Squamous Cell
Share to Chromosome Aberrations

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 29422544
DOI: 10.1038/emm.2017.265
PMCID: PMC5903820

Genes

BRCA2
FAT1
HRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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