Article
High-resolution genomic profiling of human papillomavirus-associated vulval neoplasia.
British journal of cancer - 16 Mar 2010
Purdie K J, Harwood C A, Gibbon K, Chaplin T, Young B D, Cazier J B, Singh N, Leigh I M, Proby C M
Abstract excerpt
BACKGROUND: The incidence of human papillomavirus-associated vulval neoplasia is increasing worldwide; yet the associated genetic changes remain poorly understood. METHODS: We have used single-nucleotide polymorphism microarray analysis to perform the first high-resolution investigation of genome-wide allelic imbalance in vulval neoplasia. Our sample series comprised 21 high-grade vulval intraepithelial neoplasia...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
